Implanted nerve stimulation device for chronic cluster headache prevention

This trial is testing the PRIMUS system, a small implanted device designed to stimulate two different nerve groups in your head at the same time. By targeting the trigeminal nerves (around your forehead and eyes) and the occipital nerves (at the back of your head), the device aims to interrupt pain signals and reduce how often and how severely cluster headaches occur. Early results in a small number of patients have shown promise, and this study will test whether this combination approach works for people with chronic cluster headaches who haven't found adequate relief through medications.

Chronic cluster headaches are severe and can be disabling, especially for people whose pain doesn't respond well to standard medications. This trial exists because researchers believe that stimulating these two nerve groups together may be more effective than treating them separately, offering hope to patients who have limited options.