Testing a new brain scan to detect early Alzheimer's disease changes

This trial is testing whether XTR006, a new type of brain imaging injection, can reliably detect tau tangles — a hallmark sign of Alzheimer's disease that builds up in the brain. Researchers want to see if this medication shows up clearly in PET scans and helps doctors identify who is developing Alzheimer's early, before symptoms become severe. The study includes people with normal thinking, those with mild memory loss, and those with Alzheimer's disease.

Currently, doctors have limited tools to detect the early brain changes of Alzheimer's while there is still time to intervene. This trial exists to see whether this new treatment could provide a clearer, more accurate way to identify these changes in people at risk, potentially helping doctors catch the disease earlier when treatment might be most helpful.