Plain-English translation of NCT07115953 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hypertension research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
SPYRAL SWYFT is testing the Symplicity Spyral system, a device that uses radiofrequency energy to reduce nerve activity in kidney arteries, which can help lower blood pressure. Researchers want to see if treating just the main kidney arteries and their first branches works as well as treating all accessible kidney arteries, while also shortening the procedure time. This is part of a larger study looking at long-term safety and effectiveness of this treatment approach.
High blood pressure that doesn't respond well to medication remains a serious health problem for many people. This trial is testing whether a streamlined version of this procedure—treating fewer arteries but in less time—can be just as effective, making it a simpler and potentially more accessible option for patients who need better blood pressure control.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo a procedure where doctors use the Symplicity Spyral system to treat the main kidney arteries and their first branches. The procedure is performed through a catheter (a thin tube) inserted into your blood vessels, similar to other heart catheterization procedures. After the procedure, you will be monitored for safety and effectiveness, with follow-up visits and blood pressure measurements to track how well the treatment works over time.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
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