Testing a magnetic brain stimulation technique for obsessive-compulsive disorder

Plain-English translation of NCT07116785 on ClinicalTrials.gov ↗ · Source last updated August 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a specialized magnetic brain stimulation technique called Deep TMS (Deep Transcranial Magnetic Stimulation) to treat obsessive-compulsive disorder (OCD). The treatment uses magnetic coils placed on the scalp to stimulate specific brain regions involved in OCD. Researchers want to see if an accelerated version of this treatment—given in concentrated doses over a short period—can safely and effectively reduce OCD symptoms.

Many people with OCD don't respond well enough to medications or traditional therapy alone. This study explores whether this magnetic brain stimulation approach might offer a helpful new option for people whose symptoms haven't improved adequately with standard treatments.

Do you qualify?

You likely qualify if…

you have been diagnosed with obsessive-compulsive disorder according to current diagnostic criteria
your OCD symptoms are moderate to severe (score of 20 or higher on a standard symptom scale)
you are an outpatient able to come to treatment sessions regularly
if you take medication for OCD, you have been on a stable dose for at least 2 months and plan to stay on it during the study
you have passed a safety screening questionnaire for magnetic brain stimulation
you are able and willing to commit to the 13-week treatment schedule

You likely don't qualify if…

you have had seizures or epilepsy in the past (except febrile seizures in infancy or seizures intentionally induced as part of another brain treatment)
you have metal implants in your head, eyes, or ears (such as cochlear implants, aneurysm clips, or neurostimulators)
you have a significant head injury history or have had brain surgery
you are at active risk for suicide or have attempted suicide in the past year
you have other unstable mental health conditions that may require medication changes during the study, or you are currently using illegal drugs

What participation looks like

You will be randomly assigned to receive either active magnetic brain stimulation or a sham (inactive) treatment, and neither you nor the researchers will know which you're receiving. Over 13 weeks, you'll attend treatment sessions structured in three phases: an intensive week with daily sessions, five weeks of once-weekly sessions, and then three final sessions spread over the remaining weeks. Each daily treatment involves three 20-minute sessions separated by one-hour breaks, taking about 2.5 hours total. You'll also have brain imaging scans at the beginning and after the main treatment phase.

AI-generated summary from trial data · Jun 11, 2026 · Not medical advice

Trial locations(1 site)

Israel

Soroka University Medical Center, Beersheba

Testing a magnetic brain stimulation technique for obsessive-compulsive disorder

What is this trial?

Do you qualify?

What participation looks like

Trial locations(1 site)

Key details

Contact the research team directly

Interested in joining?