Plain-English translation of NCT07123467 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether cannabidiol (a compound from cannabis, also known as CBD) combined with cognitive behavioral therapy can help reduce anxiety in adults aged 18–45. Cognitive behavioral therapy is a proven talk therapy that teaches you skills to manage anxious thoughts and feelings. Researchers want to see if adding this medication helps the therapy work better and changes how your brain processes emotions.
Generalized anxiety disorder affects many people, and while cognitive behavioral therapy works, some people don't improve as much as they'd like. This study explores whether this medication might help people learn and benefit from therapy more effectively.
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You would attend sessions over 5 weeks where you receive cognitive behavioral therapy—learning practical skills to manage anxiety—while also taking either the medication or a placebo (inactive pill) twice daily. The study includes brain imaging (MRI scans) before and after treatment to measure how the medication affects your brain's response to emotions. You'll also complete questionnaires about your anxiety symptoms and provide blood samples so researchers can measure medication levels in your body.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States