Plain-English translation of NCT07125027 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new program called Move-MORE that combines mindfulness practice, physical activity, and motivational coaching to help people with sciatica—nerve pain that radiates from the lower back down into the leg. The researchers developed this program because many people with this type of pain don't get relief from surgery or medications alone, and they wanted to create a non-invasive treatment option. The study will check whether the program is practical, acceptable to patients, and helps reduce pain and improve quality of life.
Sciatica and nerve pain in the lower back and leg can be long-lasting and difficult to treat with surgery or medications. This trial exists to test whether combining mindfulness with physical activity and supportive coaching might offer people a new way to manage their pain and reclaim their lives.
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You would attend a weekly 2-hour virtual class for 8 weeks where you'll learn mindfulness and physical activity techniques tailored to your condition. Between classes, you'll practice the program 4–5 times per week on your own using your phone, tablet, or computer. You'll also wear a small activity tracker around the clock and answer a brief daily survey about your pain. You'll visit the study site twice in person and have a follow-up visit 3 months after the program ends. Throughout the study, you'll complete questionnaires about your pain, mood, and how the program is working for you.
AI-generated summary from trial data · Aug 27, 2026 · Not medical advice
United States