Plain-English translation of NCT07125209 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ovarian Cancer research guide →This study looks at how carboplatin and paclitaxel chemotherapy—the standard drugs used to treat advanced ovarian cancer—might affect your thinking, memory, and mental sharpness. Researchers want to understand whether the medication causes any changes in cognitive function and how significant those changes might be. They'll test your thinking abilities at several points during and after your treatment.
Many cancer patients report feeling foggy or having trouble concentrating during and after chemotherapy—a problem sometimes called 'chemo brain.' This study exists to better understand whether and how this medication affects cognitive function, so doctors can eventually help patients manage these side effects more effectively.
You likely qualify if…
You likely don't qualify if…
You would complete cognitive tests and fill out surveys about your thinking and overall quality of life at four timepoints: before you start chemotherapy, after three rounds of treatment, when you finish all chemotherapy, and six months later. The cognitive tests include word memory tasks, speed-of-thinking exercises, and verbal fluency tests. Most visits would happen at your regular cancer clinic appointments, so they fit naturally into your existing treatment schedule.
AI-generated summary from trial data · Sep 5, 2026 · Not medical advice
United States
Sponsor
University of Wisconsin, Madison
Enrollment target
~18 participants
Started
April 2026
Primary completion
December 2027
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in August 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Supportive Oncology
UW Carbone Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.