Plain-English translation of NCT07125274 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are looking for new biomarkers—signs in your blood, urine, and stool that could help diagnose tuberculosis more easily and reliably. Right now, tuberculosis diagnosis often requires patients to produce sputum (phlegm), which can be difficult or impossible for some people. This study aims to find alternative ways to diagnose the disease using simpler, non-invasive samples.
Many people with tuberculosis cannot produce sputum samples, which makes diagnosis harder and can delay treatment. This study hopes to develop faster, easier diagnostic tests that would help doctors identify tuberculosis in more patients, including those who struggle with traditional sputum-based testing.
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You will visit the research center once and provide samples of blood, urine, stool, and sputum (if possible). This is a simple, one-time collection—there are no additional tests, procedures, or invasive examinations beyond these sample collections. Your regular tuberculosis care and diagnostic procedures will continue as planned, unaffected by the study.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Germany
Enrollment target
~100 participants
Started
June 2025
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Thomas Theo Brehm, Dr. med.
Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.