Imaging scan to detect amyloid buildup in the heart

This trial is testing whether two types of imaging scans—using radioactive tracers called 18F-AV45 and 11C-PIB—can reliably detect amyloid protein deposits in the heart. Researchers will give you a small injection of one of these tracers and then perform PET/CT or MRI imaging to see how well the scan shows amyloid buildup. The goal is to understand how accurate these scans are for diagnosing and monitoring cardiac amyloidosis.

Cardiac amyloidosis is a serious condition where abnormal protein builds up in the heart muscle, but it can be hard to detect and confirm. This study aims to determine whether these specialized imaging scans are reliable tools that doctors can use to diagnose the disease earlier and track how it changes over time.