Plain-English translation of NCT07133438 on ClinicalTrials.gov ↗ ·
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Retinal vein occlusion is a condition where a blood vessel in the back of your eye becomes blocked, causing fluid buildup and vision loss. This trial is testing whether mecobalamin, a form of vitamin B12, can work together with standard eye injections to improve healing and protect nerve cells in your eye better than injections alone.
While the standard eye injections work well at first, the improvement often doesn't last without repeated injections, and they don't help repair the nerve damage that occurs. Researchers believe adding this medication could both reduce swelling and help your eye's nerve cells heal better over time.
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You will receive eye injections once a month for three months, then additional injections only if needed based on your eye's response. At the same time, you will take three oral capsules daily (either the vitamin B12 supplement or a matching placebo) for 6 months. You will have regular eye exams to measure your vision and retinal swelling throughout the study period.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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