Plain-English translation of NCT07139626 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying five blood markers (SLPI, Serpin E1, CXCL10, CXCL13, and Properdin) to see if they can predict when patients with chronic heart failure will also develop kidney problems. Right now, doctors use general tests like creatinine to monitor kidney health, but these five markers may give earlier or more specific warnings when the heart and kidneys are damaging each other.
When the heart and kidneys weaken together, it's harder to treat and can be life-threatening. Current blood tests don't specifically measure the heart-kidney connection, so doctors need better early warning signs to catch and treat this condition before it becomes severe.
You likely qualify if…
You likely don't qualify if…
You'll come in for an initial blood draw and heart function test. If you're in the validation phase, you'll return for follow-up visits over 12 months so researchers can track whether your kidney function changes and see if the blood markers predicted that change. The study compares people whose kidneys stay healthy to those who develop kidney problems, to learn whether these five markers can spot the problem early.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
China