Plain-English translation of NCT07140757 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is studying radiofrequency ablation (RFA), a procedure that uses heat energy delivered through a needle to shrink or eliminate thyroid nodules and small thyroid cancers. Doctors guide the needle using ultrasound imaging to target the abnormal tissue. The study will track how well the treatment works, how it affects patients' quality of life, and what side effects occur.
Some people with thyroid nodules or early-stage thyroid cancer want to avoid surgery, or are not healthy enough for an operation. This treatment offers a less invasive option that may help shrink nodules and treat cancer while preserving more of the healthy thyroid gland.
You likely qualify if…
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You would receive the radiofrequency ablation procedure at M.D. Anderson Cancer Center, guided by ultrasound imaging. After the procedure, you would return for follow-up appointments where doctors use ultrasound to monitor how your thyroid nodule is shrinking over time. You would also complete surveys about your quality of life and any side effects you experience.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States
Enrollment target
~50 participants
Started
August 2025
Primary completion
December 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Victoria E Banuchi, MD
M.D. Anderson Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.