Two surgical approaches for treating bleeding between brain layers

Plain-English translation of NCT07144423 on ClinicalTrials.gov ↗ · Source last updated February 2026 · Translation generated August 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing two different surgical approaches to treat chronic subdural hematoma — a condition where blood pools between your brain and its protective outer lining. One approach uses a special viewing camera (neuroendoscope) to help surgeons see and remove the blood more thoroughly. The other is a more traditional drainage method. The study wants to find out which approach works better and has fewer complications.

Chronic subdural hematoma is a common and serious condition that can cause brain damage or death if not treated, but doctors aren't sure which surgical method gives patients the best long-term results. This study aims to establish the best standard approach for treating this condition.

Do you qualify?

You likely qualify if…

you are between 18 and 90 years old
you have been diagnosed with chronic subdural hematoma confirmed by CT or MRI scan
you are experiencing symptoms or neurological problems related to the condition
you are able to commit to follow-up visits for 3 months after surgery
you can provide written informed consent (or your family can on your behalf if needed)

You likely don't qualify if…

you have had surgery for this condition in the past 6 months
you have had previous brain surgery for any other reason
you have severe bleeding disorders or are at high risk for dangerous bleeding
you have serious medical conditions that would make surgery unsafe or prevent you from completing follow-up care
you are a woman of childbearing age without a confirmed negative pregnancy test

What participation looks like

If you join this study, you will be randomly assigned to receive one of two surgical drainage procedures. One group will have surgery using an endoscope camera to help visualize and remove the blood collection, while the other group will have traditional burr-hole drainage. After your surgery, you will need to come back for a follow-up visit 3 months later so researchers can check how well the procedure worked and monitor your recovery.

AI-generated summary from trial data · Aug 22, 2026 · Not medical advice

Trial locations(24 sites)

China

Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing Municipality

First Affiliated Hospital of Xiamen University, Xiamen, Fujian

Jiangmen Central Hospital, Jiangmen, Guangdong

Shantou central hosital, Shantou, Guangdong

People's Hospital of Longhua, Shenzhen, Shenzhen, Guangdong