Plain-English translation of NCT07146412 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a personalized lifestyle program can help prevent or delay dementia in older adults who are at higher risk. Researchers will first assess your individual dementia risk using family history, genetic information, blood tests, and lifestyle factors. If you're at high risk, you'll be offered a multimodal lifestyle intervention—meaning a combined program addressing multiple areas of health—designed to help reduce your risk of developing cognitive problems.
Dementia treatments work best when started early, before memory problems begin. Research shows that lifestyle changes can significantly delay dementia in people at high risk, but we need to better understand how to deliver these programs effectively and who benefits most.
You likely qualify if…
You likely don't qualify if…
You'll start with baseline assessments including cognitive testing, blood work to measure dementia-related biomarkers, lifestyle questionnaires, and physical performance tests. Researchers will then determine your individual dementia risk. If you're at high risk, you'll be invited to participate in a multimodal lifestyle intervention—which may include recommendations around diet, exercise, cognitive training, sleep, and social engagement. You'll complete follow-up surveys, cognitive assessments, and provide additional blood samples throughout the study to track changes in your risk factors and dementia markers.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States