Plain-English translation of NCT07147218 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Major Depressive Disorder research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing an accelerated version of transcranial magnetic stimulation (TMS) — a non-invasive brain stimulation treatment for depression. Instead of spreading sessions over weeks, this study delivers 36 treatments in just 5 consecutive days (6–8 sessions per day). Researchers want to see if this faster approach is well-tolerated and effective for people with major depressive disorder who haven't improved enough with antidepressant medication.
Standard TMS requires many weeks of treatment, which can be inconvenient and may delay relief from depression. This trial explores whether the same total number of treatments, delivered much more intensively over just 5 days, could work just as well—or better—while being easier to fit into a patient's life.
If you qualify and enroll, you will come for treatment 5 days in a row. Each day, you'll receive 6 to 8 TMS sessions (the exact number may vary). During each session, a magnetic coil is placed against your scalp to stimulate brain activity—it's non-invasive and you remain awake. You'll also complete questionnaires and assessments to track how you're feeling throughout and after the treatment week.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
United States
Sponsor
Neuronetics
Enrollment target
~50 participants
Started
August 2025
Primary completion
December 2027
Age range
15 Years and older
Last updated on clinicaltrials.gov in June 2026.