Testing a simple cervical fluid test to screen for endometrial cancer

Researchers are studying a test called CYTOMARK that measures certain protein markers in cervical fluid to detect endometrial cancer — a cancer of the uterine lining. This study will determine if this simple, non-invasive test can accurately identify endometrial cancer in postmenopausal women who have abnormal uterine bleeding. The goal is to create an algorithm (a decision-making tool) to help doctors use the test to screen for this cancer.

Currently, detecting endometrial cancer often requires more invasive procedures. This trial seeks to develop a simpler, non-invasive screening tool that could catch endometrial cancer earlier in women at higher risk, potentially improving outcomes and reducing the need for more uncomfortable diagnostic procedures.