Plain-English translation of NCT07152197 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a structured 8-week resistance exercise program focused on leg strengthening can help young adults with Charcot-Marie-Tooth disease (CMT) build stronger, healthier muscles and improve their ability to move and function in daily life. The research team will compare results between people with CMT who do the program and healthy people without CMT who do the same program, measuring changes in muscle quality, strength, balance, and overall quality of life.
Charcot-Marie-Tooth disease causes progressive weakness and shrinking of muscles, especially in the legs and feet, which makes everyday activities harder. While strength training has helped other groups of people, doctors don't yet know if it's safe and effective for young adults with this condition—so this trial will fill that gap.
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If you join this study, you will attend supervised exercise sessions 3 times per week for 8 weeks, focusing on progressive strengthening exercises for your legs. Before you start and after you finish, the research team will perform various assessments—like ultrasound imaging of your leg muscles, strength tests, balance and walking tests, and questionnaires about your quality of life—to see how the program affects your muscles and daily function.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
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