Plain-English translation of NCT07153458 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are looking for new ways to detect colon cancer earlier by studying blood and tissue samples from three groups of people: those diagnosed with colon cancer, those with precancerous growths called high-grade dysplasia adenomas, and those with no colon disease. This study is observational, meaning you'll participate in your normal medical care (surgery or colonoscopy) and researchers will collect extra blood and tissue samples to search for biological markers—signs in your blood that might predict or diagnose colon cancer.
Current methods for detecting colon cancer are not always caught early enough. By identifying new biomarkers in blood samples, doctors hope to develop simpler, non-invasive blood tests that could catch colon cancer or precancerous changes before they become more serious.
You likely qualify if…
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If you join this study, you'll participate as part of your regular medical care—either a scheduled colonoscopy or colon surgery. Before your procedure, you'll meet with researchers, answer questions about your medical history, and give a blood sample. If you're having surgery, you'll give another blood sample at a follow-up visit, and researchers will collect small pieces of tissue that are removed during your surgery but would otherwise be discarded. The study involves no extra procedures beyond what you're already scheduled to have.
AI-generated summary from trial data · Aug 11, 2026 · Not medical advice
Italy
Sponsor
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Collaborators
University of Bari Aldo Moro
Enrollment target
~60 participants
Started
December 2025
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Pasqua Letizia Pesole, Biologist
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.