Plain-English translation of NCT07154173 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying the bacteria that naturally live in your gut and in tumors to understand why some colorectal cancers spread to other parts of the body and others don't. This research may help doctors predict which cancers are more likely to spread and develop better treatments in the future.
About half of people with colorectal cancer eventually develop cancer spread, but doctors don't yet have reliable ways to predict who will be affected. This study aims to fill that gap by exploring whether certain bacteria patterns can serve as early warning signs of cancer spread.
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If you qualify, you would provide stool samples before surgery and allow doctors to collect small tissue samples during your colorectal cancer surgery—samples from the tumor itself, nearby healthy tissue, and (if your cancer has spread) tissue from where it has spread. The researchers will then analyze the bacteria in these samples using advanced laboratory methods to look for patterns that might predict cancer spread. The study involves about 300 participants total across three groups: healthy volunteers, people with colorectal cancer that hasn't spread, and people whose cancer has spread.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
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