Plain-English translation of NCT07154199 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing transcranial ultrasound stimulation (TUS)—a non-invasive procedure that uses sound waves to stimulate a specific area of the brain—to see if it can improve thinking and memory problems in people dealing with long-lasting brain fog after COVID-19. Researchers believe brain fog may be caused by changes in a particular brain region, and this treatment aims to help that region work better.
Long COVID brain fog can be deeply frustrating and disabling, affecting people's ability to work and enjoy daily life. Current treatments are limited, so researchers are exploring whether this non-invasive sound wave treatment could offer relief by targeting the brain regions involved in thinking and memory.
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You will have two main visits. On Day 1, you'll complete thinking and memory tests, have a brain scan, and answer questions about your brain fog symptoms. On Day 2, you'll receive either the actual sound wave treatment or a sham (placebo) version—neither you nor some of the study team will know which one you get. After the treatment, you'll have another brain scan and repeat the thinking tests. The entire study takes place over just two days.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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