Plain-English translation of NCT07154511 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing whether , a naturally derived supplement related to a substance your body produces from fiber, can help improve thinking and memory in people with Parkinson's disease who are experiencing cognitive changes. works differently than current treatments by potentially helping brain cells use energy more efficiently and supporting communication between your gut and brain. Half of participants will receive the medication while the other half receive a placebo (inactive pill) to see if the treatment actually works.
Many people with Parkinson's disease develop thinking and memory problems that can progress to dementia, and current treatments don't work well for these cognitive changes. Researchers believe this medication might help by improving how brain cells function and supporting the natural connection between gut health and brain health.
You likely qualify if…
You likely don't qualify if…
You will take either the medication or a placebo pill three times daily for about 3 months. You'll attend study visits for assessments of your thinking and memory, and you may have an MRI brain scan and blood tests. The study is being conducted to see whether the medication is safe and whether it helps improve cognitive symptoms in people with Parkinson's disease.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States