Plain-English translation of NCT07157631 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether —a medication that helps prevent excessive bleeding—can reduce blood loss during liver transplant surgery in adults with severe liver disease. Liver transplants are complex operations where patients often bleed heavily during surgery. This study wants to see if giving this medication at the start of surgery can make transplants safer by reducing the need for blood transfusions.
Liver transplant surgery is life-saving but carries a serious risk of dangerous bleeding during and after the operation. While surgical techniques have improved over time, many patients still lose significant amounts of blood. This medication has shown promise in other types of surgery, and researchers want to know if it can help liver transplant patients too.
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If you join this study, you will be randomly assigned to receive either the clot-prevention medication or a placebo (a harmless saline solution that looks identical) given intravenously once, at the beginning of your liver transplant surgery. You will not know which group you are in. Your care during and after surgery will be the same as standard liver transplant care, and the research team will monitor you for bleeding, blood clots, and other outcomes as part of normal post-transplant follow-up.
AI-generated summary from trial data · Jun 29, 2026 · Not medical advice
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