Plain-English translation of NCT07158242 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether a new medication called can safely and effectively treat children ages 2–17 who have moderate to severe ulcerative colitis and haven't responded well to standard treatments. Children will receive this medication through an IV infusion first, then continue with injections at home. The trial will track how well the medication works and watch for any side effects.
Ulcerative colitis in children can be serious and difficult to treat, especially when standard medications don't work well enough. This trial is testing whether this new treatment option can help children whose bowel inflammation isn't controlled by existing therapies.
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You would start with an intravenous infusion of the medication at a clinic or hospital, then continue treatment with self-administered injections. The study involves regular visits to monitor how well the medication works and check for side effects over several months. Your child would be randomly assigned to receive one of two doses to help researchers figure out which works best and is safest.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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