Plain-English translation of NCT07159334 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After hemorrhoid removal surgery, managing pain is one of the biggest challenges patients face. This trial is testing whether or glyceryl trinitrate (GTN) ointment—when applied directly to the surgical wound three times daily—works better to reduce pain and speed up healing. Researchers will track your pain levels over four weeks and measure how quickly your wound heals.
Severe pain after hemorrhoid surgery can make it hard to move around and recover normally. While both of these topical medications have shown promise for pain relief, doctors still aren't sure which one works better or is safer for patients in the long term.
You likely qualify if…
You likely don't qualify if…
You will first have hemorrhoid removal surgery under anesthesia at Mayo Hospital in Lahore. After surgery, you'll be randomly assigned to receive either lignocaine cream or GTN ointment, which you'll apply to the surgical area three times daily along with standard care (sitz baths and stool softeners). Over the next four weeks, you'll report your pain levels at multiple time points—at 6, 12, 24, and 48 hours after surgery, then at 1, 2, 3, and 4 weeks—using a simple pain scale. Researchers will track how your wound heals and how satisfied you are with your pain relief.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
Pakistan