Plain-English translation of NCT07159880 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing letrozole, a medication that helps trigger ovulation in women with polycystic ovary syndrome (PCOS) who are trying to become pregnant. The study compares two different treatment schedules: taking the medication for 5 days versus taking it for 10 days. Researchers want to see which approach works better and is safer for helping women ovulate and achieve pregnancy.
PCOS is one of the most common reasons women struggle to ovulate and become pregnant. While this medication is already widely used and proven to help, doctors are still unsure about the best length of treatment—whether a longer course might help more women successfully ovulate and get pregnant.
You likely qualify if…
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If you join this trial, you will be randomly assigned to take the medication either for 5 consecutive days or for 10 consecutive days starting on day 2 of your cycle. Throughout the study, you will have transvaginal ultrasounds and blood or urine tests to monitor whether you are ovulating. The trial will track your ovulation response and whether you become pregnant, allowing researchers to compare which treatment length works best.
AI-generated summary from trial data · Jul 9, 2026 · Not medical advice
Brazil
Sponsor
GABRIEL MONTEIRO PINHEIRO
Enrollment target
~20 participants
Started
September 2025
Primary completion
July 2026
Age range
18 Years – 40 Years
Sex
Female only
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Katherine Ann R Miller, Medical student
Universisty of Santo Amaro
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.