Plain-English translation of NCT07161245 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a structured 8-week program combining tailored exercise, nutritional guidance, and psychological support can help reduce the severe fatigue that many people with primary biliary cholangitis experience. Fatigue is the most bothersome symptom of this rare autoimmune liver disease for many patients, yet current medications don't treat it effectively. This study will compare the new program to standard care to see if a comprehensive, personalized approach works better.
Up to 60% of people with primary biliary cholangitis suffer from debilitating fatigue—described as brain fog and lack of energy—that disrupts work, family, and social life. No medication currently treats this fatigue effectively, so researchers are testing whether a combined approach of exercise, nutrition, and counseling might help where drugs have failed.
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If you are randomly selected for the treatment group, you will participate in an 8-week program tailored to your specific health, life situation, and ability to participate. This includes personalized exercise sessions, guidance on nutrition, and counseling to help manage stress and anxiety. The comparison group will receive standard care with general recommendations about physical activity, diet, and stress management. Throughout the study, researchers will also take blood samples and ask questions to understand why fatigue happens in this disease and how the program might help.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
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