Plain-English translation of NCT07163650 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This study tests a medication called efsubaglutide alfa in people who have had weight-loss surgery but are still struggling with obesity six months later. Researchers want to see if adding this medication—along with diet and exercise guidance—helps people reach a healthier weight and improves related health problems like high blood pressure or diabetes. Half of participants will receive the medication for 24 weeks, while the other half will receive diet and exercise support alone.
Weight-loss surgery helps many people, but some patients don't lose as much weight as they'd hoped or regain weight over time. This trial is testing whether this medication can bridge that gap and help more people achieve their weight-loss goals after surgery.
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If you join this study, you'll be randomly assigned to either receive the new medication or to receive diet and exercise guidance alone. Both groups will receive support with healthy eating and physical activity throughout the 24-week study. If you're in the medication group, you'll receive injections or doses of the treatment at the study center. You'll have regular visits to check your weight, health markers, and how well the treatment is working, and the study team will monitor you for any side effects.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
China
Phase
Post-approval monitoring
Sponsor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Enrollment target
~60 participants
Started
September 2025
Primary completion
November 2026
Age range
18 Years – 55 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
wenhuan Feng
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.