Plain-English translation of NCT07164300 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During heart surgery that uses a heart-lung machine, patients often bleed more than usual and may need blood transfusions. This trial is testing tranexamic acid, a medication that helps reduce bleeding by stabilizing blood clots. Researchers want to find out which dose — a lower one, a medium one, or a higher one — works best and causes the fewest side effects.
Doctors know this medication helps reduce bleeding and the need for transfusions in heart surgery, but no one agrees on the best dose to give. Some evidence suggests lower doses might work just as well as higher doses but with fewer complications, but this hasn't been properly studied yet.
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If you join this trial, you would receive the bleeding prevention medication as part of your normal heart surgery care — you won't need extra visits or tests beyond your regular surgery preparation and follow-up. You'll be randomly assigned to receive one of three doses of the medication right after you fall asleep for surgery. The research team will monitor how well the medication works at preventing bleeding and check your blood levels to measure how long it stays active in your body.
AI-generated summary from trial data · Sep 17, 2026 · Not medical advice
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