Plain-English translation of NCT07166874 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a gluten-free diet can help people with ankylosing spondylitis—a chronic disease that causes inflammation in the spine and joints. Researchers believe that gluten may trigger a chain reaction in the gut that increases inflammation throughout the body. By removing gluten from the diet for 8 weeks, this study will measure whether patients experience less pain, better function, and improved quality of life.
There is growing evidence that gut health may play a major role in ankylosing spondylitis, but no study has directly tested whether removing gluten—which is known to affect gut health—actually improves symptoms. This research aims to fill that gap so doctors can give patients clear dietary advice based on solid evidence.
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If you are enrolled, you will be randomly assigned to either continue eating normally or follow a gluten-free diet for 8 weeks while taking your regular medications. Throughout the study, researchers will measure your inflammation levels, pain, and quality of life using blood tests and questionnaires. The study will last 8 weeks, and you will need to attend visits where they collect samples and assess how you are feeling.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Turkey (Türkiye)