Plain-English translation of NCT07167329 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
The BELIEVE-VHL trial is studying how well (a medication called WELIREG) works for people with von Hippel-Lindau syndrome who have tumors that need treatment. This study will track how the medication affects your tumors, how your body responds to it, and how it impacts your everyday life and well-being.
Von Hippel-Lindau syndrome causes multiple tumors in different parts of the body, and there is a need to understand how well this medication works in real-world patients and which factors influence how well people respond to treatment. This study will also help doctors understand the costs and benefits of using this treatment compared to standard care.
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You will take the medication by mouth daily as prescribed. The study team will monitor you regularly over time, checking your blood work and imaging scans to see how your tumors respond, watching for side effects, and asking you questions about your quality of life and how you're feeling. You may also need blood tests to monitor your red blood cell counts and oxygen levels, and some patients may receive additional support if anemia develops during treatment.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
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