Plain-English translation of NCT07170462 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether can help restore healthy gut bacteria and reduce inflammation in people with Crohn's disease. You would take a freeze-dried supplement (or a matching placebo) every day for 10 weeks. Researchers want to see if the natural compounds in cranberries—polyphenols and fiber—can help your gut microbiome (the community of bacteria in your intestines) heal and improve your quality of life.
Crohn's disease disrupts the balance of bacteria in the gut, which contributes to inflammation and symptoms—even when people are taking medications. Early research suggests that plant-based foods like cranberries may help restore healthy gut bacteria, so this trial is designed to test whether this simple dietary approach could work for people with Crohn's.
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You would take part in this study for 15 weeks total. For the first 10 weeks, you would consume one serving of either or placebo powder every day—whichever group you're randomly assigned to. You don't know which one you're taking (it's double-blinded, meaning both you and the researchers don't know which is real). At four time points (at the start, week 6, week 10, and week 14), you would complete questionnaires about your symptoms and quality of life, and provide stool samples so researchers can analyze your gut bacteria. After the 10-week supplement period, you continue with a 4-week follow-up phase to see if any changes last.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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