Plain-English translation of NCT07173543 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 2 Diabetes research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a non-drug treatment called intermittent hypoxia—which involves brief cycles of reduced oxygen followed by normal oxygen—can improve brain blood flow and cognitive function in older adults with type 2 diabetes. The treatment lasts about 50 minutes per session. Researchers believe this approach may help protect brain health in people at higher risk for memory loss and cognitive decline.
Older adults with type 2 diabetes face a significantly higher risk of cognitive decline and dementia compared to those without diabetes. Current medical treatments have limited ability to prevent this decline, so researchers are exploring non-medication approaches to protect brain health and blood flow in this vulnerable population.
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If you enroll, you will visit the research facility where you will receive either the intermittent hypoxia treatment or a control treatment (normal oxygen) over a single 50-minute session. The treatment involves wearing a mask that alternates between normal air and slightly reduced oxygen levels in brief cycles. You will also complete thinking and memory tests, and researchers will measure your brain blood flow before and after the session.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
United States
Sponsor
Darren P Casey
Collaborators
American Diabetes Association
Enrollment target
~80 participants
Started
September 2025
Primary completion
June 2028
Age range
60 Years – 85 Years
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Darren Casey, PHD
Darren P Casey
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