Testing radiation plus two medications to shrink liver cancer before surgery

This trial is testing whether combining radiation therapy with two medications—QL1706 (an immunotherapy) and bevacizumab (a medication that blocks blood vessel growth in tumors)—can shrink liver cancer that cannot be surgically removed right now. The goal is to see if this combination treatment can make the cancer small enough that doctors can then operate. Researchers will compare this three-part approach against using just the two medications without radiation.

Many patients with liver cancer cannot have surgery immediately because their tumors are too large or in difficult positions. This medication combination may help shrink these tumors, but researchers want to know whether adding radiation therapy makes it even more effective at making surgery possible.