Plain-English translation of NCT07182058 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing the Sphere V3.0, a non-invasive brain stimulation device designed to help reduce motor symptoms (like tremor and stiffness) in people with Parkinson's disease. The device uses mild electrical pulses delivered through electrodes placed on your scalp to stimulate the brain regions that control movement. Everything happens remotely—you'll use the device at home and connect with the research team through video calls.
Current Parkinson's treatments don't work equally well for everyone, and some people experience side effects. This trial is exploring whether this treatment could offer a new option for people whose movement symptoms aren't fully controlled by medication alone.
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You'll receive the Sphere V3.0 device by mail with training videos to help you set it up. A researcher will guide you through a video call to show you how to place the electrodes on your scalp correctly. Then, you'll use the device for 13 minutes each weekday (Monday through Friday) for 3 weeks—15 sessions total. During this time and for 3 weeks after, you'll submit weekly check-in surveys, and the research team will ask you to record videos of your movements (like walking and arm movements) for computer analysis. You'll have 24/7 access to a support hotline if you have any concerns.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United States