Plain-English translation of NCT07184931 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn's Disease research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing a new medication called to see if it can help people with moderate to severe Crohn's disease who haven't benefited from existing treatments. About 980 people across multiple countries will receive either the medication or a placebo through injections under the skin. The goal is to find out if this treatment is safe and effective at reducing Crohn's symptoms.
Many people with Crohn's disease don't respond well enough to current treatments, or their bodies stop responding over time. This trial is exploring whether this new approach can help patients who have run out of other options.
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You would receive injections under the skin either of the new medication or a placebo over a 12-week period, with the possibility of extending to 35 weeks total if you continue to a follow-up maintenance study. You'll have multiple clinic visits (up to 8–15 depending on which part of the study you're in) for blood work, symptom checks, and assessments of how well the treatment is working. The study team will carefully monitor you for any side effects throughout the process.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
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