Plain-English translation of NCT07186660 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This is a 12-week research study testing a new medication called designed to help your body use insulin more effectively. If you have type 1 diabetes and use a closed-loop automated insulin pump, this medication may help improve your blood sugar control and possibly reduce how much insulin you need. Researchers will monitor your heart health, blood sugar levels, and how well the treatment works.
Even with modern insulin pumps, many people with type 1 diabetes struggle to maintain healthy blood sugar levels and require high doses of insulin. This medication is designed to make your own body's cells more sensitive to insulin, which could help you achieve better control with less insulin.
You likely qualify if…
You likely don't qualify if…
You will have three in-person visits at the University of Virginia Medical Center: a screening visit, a baseline visit, and a final visit after 12 weeks. During the 12-week study period, you'll take either the new medication or a placebo tablet daily, continue wearing your insulin pump and a study glucose monitor, check your ketone levels each morning with a provided meter, and report any health issues to the research team. The study team will contact you regularly to check on your health and how you're managing with the medication.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States