Comparing two ultrasound methods to measure liver fat

Plain-English translation of NCT07192159 on ClinicalTrials.gov ↗ · Source last updated September 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a new ultrasound method called DeepUSFF that measures how much fat is in your liver. Researchers want to see how well this quick ultrasound technique compares to MRI scanning, which is currently considered very accurate but is expensive and hard to access. If this ultrasound works well, it could become a cheaper, easier way to check on liver fat in people with fatty liver disease.

Fatty liver disease is common and doctors need accurate ways to measure how much fat is in the liver to plan treatment and monitor progress. While MRI scanning is very accurate, it's expensive and not available everywhere. This study aims to see if a simpler, faster ultrasound method could work just as well.

Do you qualify?

You likely qualify if…

you are 18 years or older
you have signs of fatty liver disease based on recent ultrasound or blood tests, or you are a potential liver donor
you are overweight (BMI of 25 or higher) or have excess belly fat, which increases the chance of fatty liver disease
you are willing to undergo two imaging scans within one week
you can understand the study and sign an informed consent form

You likely don't qualify if…

you have drunk significant amounts of alcohol in the past 2 years
you have chronic liver disease, hepatitis B, hepatitis C, or other known chronic liver conditions
you have signs of liver failure such as low protein levels, abnormal clotting, or high bilirubin in your blood
you have a history of advanced liver problems like internal bleeding, fluid buildup, or liver cancer
you are pregnant, cannot cooperate with imaging, have a cardiac pacemaker, or have other conditions that would prevent safe MRI scanning

What participation looks like

You would visit a hospital or imaging center and have two non-invasive imaging scans performed within one week of each other. First, you'll have a quantitative ultrasound exam of your liver that takes about 10–15 minutes and involves taking multiple measurements while holding your breath. Then, within 7 days, you'll have an MRI scan of your liver that also uses breath-hold sequences. Both scans are painless and non-invasive, and researchers will compare the results to see how well the ultrasound method matches the MRI method.

AI-generated summary from trial data · Jun 24, 2026 · Not medical advice

Trial locations(2 sites)

United States

southwoods imaging (Northeastern Ohio Radiology Research and Education Fund ), Boardman, Ohio

South Korea

Seoul National University Hospital, Seoul, Seoul