Plain-English translation of NCT07192679 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
MAGNIFY is a research study that tests two advanced ways of measuring lung function in people with cystic fibrosis: special lung imaging scans called hyperpolarized gas MRI (which takes pictures of air in your lungs after you breathe in a harmless gas) and a breathing test called multiple breath washout. These tests are designed to help doctors understand changes in lung health over time in greater detail than standard tests alone.
Current lung function tests don't always catch early changes in cystic fibrosis. This study aims to find better ways to measure lung damage and track how well treatments are working, so doctors can spot problems sooner and help people stay healthier longer.
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Depending on which group you join, you will visit the hospital between 2 and 4 times over 1 to 3 years. During each visit, you will complete standard breathing tests, breathe in a harmless gas while special MRI machines take pictures of your lungs, and do a breathing test that measures how quickly your lungs clear air. Each visit takes several hours, and the study team will explain everything before you begin.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United Kingdom
University of Sheffield
Enrollment target
~60 participants
Started
February 2024
Primary completion
June 2029
Age range
1 Year and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jim Wild, Professor
Sheffield Teaching Hospitals NHS Foundation Trust
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.