Plain-English translation of NCT07194590 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether , a natural compound related to soy, can help improve blood vessel function in postmenopausal women who have chronic kidney disease (stages 3-4). Women with kidney disease face higher risks of heart and blood vessel problems, especially after menopause. This trial aims to see if taking daily might help protect blood vessel health in this group.
Chronic kidney disease damages blood vessels and increases heart disease risk, and menopause makes this problem worse because of hormonal changes. Hormone replacement therapy, which is sometimes used to address menopause, carries its own risks. Researchers are investigating whether this medication might offer a safer alternative to help protect blood vessel health.
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If you qualify, you will be randomly assigned to take either the supplement or a placebo (inactive pill) — 2 capsules by mouth each day. You'll need to maintain stable weight throughout the study and attend visits for blood pressure checks, blood tests, and special imaging or ultrasound tests to measure how well your blood vessels are working. The study will monitor your kidney function, heart health, and blood vessel function over the course of the trial.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
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