Plain-English translation of NCT07197138 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a brain stimulation treatment called intermittent theta-burst stimulation (iTBS) for people living with depression that hasn't improved enough with medication, who also have long COVID symptoms. Researchers want to see if this non-invasive magnetic stimulation can reduce depression and improve the blood markers that show inflammation in the body. The study compares two different schedules: one session per day over six weeks, or six sessions per day over five days.
Many people with depression and long COVID don't get enough relief from medication alone, and both conditions involve inflammation in the body. This trial explores whether this treatment can help reduce depression symptoms while also lowering the inflammatory markers that may contribute to long COVID fatigue and other lingering problems.
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If you join this study, you'll be randomly assigned to receive either one magnetic stimulation session per day over six weeks, or six sessions per day over five consecutive days (both deliver 30 total sessions). Each session takes about three minutes and targets a specific area of your brain involved in mood. You'll have blood drawn at the start, right after treatment ends, and three days later to measure inflammation markers, and you'll complete questionnaires about your depression, fatigue, sleep, and other symptoms at baseline, shortly after treatment, and again at three months.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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