Plain-English translation of NCT07199088 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When your heart isn't pumping well, fluid builds up in your body and you may need hospitalization. This trial tests whether adding acetazolamide to your regular heart failure medicines helps remove that extra fluid better and gets you home sooner. Researchers will compare it to another medication called metolazone to see which one is safer and more effective.
Hospitalized heart failure patients often struggle with excess fluid that doesn't respond well to standard treatments alone. Doctors want to know if either of these additional medications can help patients recover faster, spend less time in the hospital, and avoid kidney damage or electrolyte problems.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will be randomly assigned to receive either acetazolamide or metolazone as an add-on to your regular heart failure medicines while you are in the hospital. Your doctors will monitor how well the medication removes fluid from your body, track your blood work to watch for any problems with your kidneys or electrolytes, and measure how long you need to stay in the hospital. The study will also watch for any side effects and compare how each medication helps you improve.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Pakistan