Plain-English translation of NCT07202247 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing three different approaches to protect your heart and metabolic health while you receive hormone therapy (androgen deprivation therapy) for prostate cancer. One group will practice time-restricted eating — eating only during an 8-hour window each day. Another group will take or , medications that help regulate blood sugar and weight. The third group will follow a heart-healthy diet with personalized guidance. All participants will continue their standard prostate cancer treatment.
Hormone therapy for prostate cancer can increase the risk of weight gain, high blood sugar, high cholesterol, and heart problems. This study wants to find out whether simple lifestyle changes or the medication can prevent these side effects and keep you healthier during treatment.
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You will be randomly assigned to one of three groups. If assigned to the time-restricted eating group, you'll fast overnight for at least 16 hours on 5 or more days per week, log your meals using a mobile app, and receive diet counseling for 6 months. If assigned to the medication group, you'll visit an endocrinologist and receive weekly injections of or for 6 months, plus dietary education. All participants will have blood tests and imaging scans throughout the 6-month study to monitor your heart health and metabolism.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States