Plain-English translation of NCT07202949 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
EAT-UP is testing whether a treatment-strength dose of an antibiotic combined with methenamine hippurate (a urinary antiseptic) works better than current standard care for women with chronic urinary tract infections. You would take the medication for 12 weeks and attend clinic visits every 4 weeks for blood, urine, and swab samples. This trial aims to find a more effective way to help women who suffer from persistent bladder and urinary pain.
Many women with chronic urinary tract infections struggle with persistent symptoms even after treatment. Researchers want to know whether using a stronger dose of antibiotic in combination with a urinary antiseptic might provide better relief than the lower doses currently used.
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If you join this trial, you will be randomly assigned to one of two groups. One group will take a stronger dose of antibiotic plus a urinary antiseptic medication; the other group will take either a lower-dose antibiotic or just the urinary antiseptic alone. You will take your assigned medication for 12 weeks and visit the clinic every 4 weeks for check-ups, where you'll answer questions about your symptoms and provide blood, urine, and swab samples to help researchers track how well the treatment is working.
AI-generated summary from trial data · Sep 5, 2026 · Not medical advice
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