Plain-English translation of NCT07209098 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether a device called the Optimizer System—implanted in the heart—can help people with moderate to severe heart failure live better lives. The study will compare people who receive this device with similar patients who don't, using medical information already collected by hospitals across the United States. Researchers want to understand how well this treatment works in real-world conditions over several years.
Many people with heart failure continue to struggle with symptoms even after taking multiple medications as prescribed. This trial exists to see whether this implanted device can provide additional benefit for patients like you whose hearts aren't pumping strongly enough, despite being on the best available medicines.
You likely qualify if…
You likely don't qualify if…
If you are selected for the treatment group, you will undergo implantation of the Optimizer System device. All participants will have their existing medical records and health outcomes tracked from the database over several years (up to 8 years of data may be reviewed). Your participation is primarily observational, meaning researchers will monitor your health information and clinical progress over time rather than requiring frequent study visits—though your regular heart care appointments will continue as usual.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States
Sponsor
Impulse Dynamics
Enrollment target
~4,200 participants
Started
November 2025
Primary completion
October 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kathy Sherwood, MBA
Impulse Dynamics
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.