Plain-English translation of NCT07213466 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This study is testing whether personalized weight loss medications work better when matched to how your body handles hunger and eating. Researchers will first figure out your unique eating pattern (whether you struggle with feeling full, emotional eating, or metabolism), then give you the medication that best fits your pattern—or suggest lifestyle changes alone—plus a 12-week support program with a therapist and dietitian.
People with bipolar disorder often struggle with weight gain as a side effect of their mood medications, but there hasn't been much research on which weight loss treatments work best for them. This study aims to find safer, more effective ways to help this group manage their weight while protecting their mental health.
You likely qualify if…
You likely don't qualify if…
You'll start with special tests to figure out your eating pattern—these include a metabolism scan, stomach function test, and a meal test where you eat as much as you want. Based on your results, you'll either receive one of three FDA-approved weight loss medications or join a lifestyle-only program, along with 12 weeks of weekly group sessions covering nutrition, exercise, and emotional eating strategies. The whole study lasts 16 weeks, with regular check-ins to monitor your safety and how well the treatment is working.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States