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Take a daily pill being tested for moderate to severe eczema | stella

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Recruiting

Testing a new daily pill for moderate to severe eczema

Plain-English translation of NCT07216027 on ClinicalTrials.gov ↗ · Source last updated July 2026 · Translation generated August 2026 · How we translate trials

Read our Atopic Dermatitis research guide →

Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.

What is this trial?

This trial is testing a new medication called to see if it can safely and effectively treat moderate to severe eczema (atopic dermatitis). You would take this medication as a daily tablet for 12 weeks and have your skin condition carefully monitored. The study will compare how people on this medication do compared to those taking a placebo (an inactive pill that looks the same).

Many people with moderate to severe eczema don't have suitable treatment options available to them. This trial is exploring whether this new medication could be a safe and effective choice for those who need better control of their itching, rashes, and skin symptoms.

Do you qualify?

You likely qualify if…

you are between 18 and 64 years old
you have been diagnosed with eczema for at least 6 months
you have moderate to severe eczema affecting at least 10% of your body
your itching is significant and affects your daily life
you do not have a suitable prescribed medication for your eczema
your body mass index is between 18 and 38, and you weigh more than 106 pounds

You likely don't qualify if…

you have an active infection that needs treatment
you have other skin conditions besides eczema
you have severe asthma that is not well controlled
you have used a tanning booth or phototherapy more than twice a week in the past 4 weeks

What participation looks like

You would take a daily tablet (either the new medication or a placebo) for 12 weeks. You'll visit the clinic 7 times during the study — on Day 1 and then at Weeks 1, 2, 4, 6, 8, and 12 — plus a final check-up at Week 16. At each visit, your skin will be examined, you'll have blood and urine tests, and you'll answer questions about your symptoms and how your eczema affects your life.

AI-generated summary from trial data · Aug 2, 2026 · Not medical advice

Trial locations(20 sites)

United States

Marvel Clinical Research, Huntington Beach, California

Metropolis Dermatology - DTLA, Los Angeles, California

Northridge Clinical Trials, Northridge, California

Clinical Science Institute, Santa Monica, California

Gsi Clinical Research, Margate, Florida

Key details

Phase

Testing effectiveness

Sponsor

Pfizer

Enrollment target

~165 participants

Started

November 2025

Primary completion

February 2028

Age range

18 Years – 64 Years

Last updated on clinicaltrials.gov in July 2026.

Contact the research team directly

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Central contact

Pfizer CT.gov Call Center

Pfizer

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View full record on ClinicalTrials.gov