Plain-English translation of NCT07217405 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether low-dose radiotherapy (a type of gentle radiation treatment) works as well as or better than corticosteroid injection (a steroid shot into the joint) for treating hand and wrist arthritis. You would receive either six low-dose radiation treatments or a standard steroid injection, and researchers would track your pain and hand function over time to see which treatment helps more.
Hand and wrist arthritis can cause significant pain and limit daily activities. While steroid injections are commonly used, researchers want to know if low-dose radiation—a treatment that has shown promise—could be an equally effective or even better option for patients.
You likely qualify if…
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If you join this study, you will be randomly assigned to receive either six low-dose radiation treatments to your hand or a corticosteroid injection—the standard treatment option. You will need to visit Mayo Clinic in Rochester, Minnesota for your treatment and follow-up visits. Throughout the study, you will complete questionnaires about your pain and hand function to help researchers understand how well each treatment works for you.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States
Phase
Post-approval monitoring
Sponsor
Mayo Clinic
Enrollment target
~165 participants
Started
December 2025
Primary completion
May 2027
Age range
50 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Tochukwu Iyke-Nzeocha
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.