Plain-English translation of NCT07219875 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research study is testing a new type of virtual reality training called Virtual Reality-Reward Training designed to help people with depression feel more pleasure and joy in their lives. The study will compare this new training to a control virtual reality program that focuses on memory instead of rewards. Researchers want to see if the reward-focused training can help improve mood and the ability to enjoy activities.
Many people with depression struggle with anhedonia—the loss of interest and pleasure in things they normally enjoy—and this symptom is often hard to treat with current medications and therapy. This study is testing whether training the brain's reward system through virtual reality might help address this specific problem.
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You would attend 13 virtual reality training sessions over 7 weeks (roughly 2 sessions per week), where you'll be immersed in either rewarding or neutral virtual environments depending on which group you're randomly assigned to. You'll also complete questionnaires and simple tests at the beginning, middle, end, and 1 month after the training finishes. The entire study takes about 3 months from start to finish.
AI-generated summary from trial data · Jul 17, 2026 · Not medical advice
United States