Plain-English translation of NCT07220512 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The BHFS Study is tracking how neoadjuvant chemotherapy—medicine given before surgery—affects older cancer patients' physical fitness and thinking abilities. Researchers will measure your frailty and cognitive function before you start chemotherapy and again after 3 or 4 rounds of treatment to see if the medication impacts how ready your body is for surgery.
Doctors know that chemotherapy is important for treating advanced ovarian and endometrial cancers, but they don't fully understand how this treatment affects older patients' overall strength, energy, and mental clarity before surgery. This study aims to fill that gap so doctors can better prepare patients and predict surgical outcomes.
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Before your first chemotherapy appointment, you'll complete some questionnaires and cognitive tests that measure your fitness level and thinking ability. After finishing 3 or 4 rounds of chemotherapy, you'll repeat these same assessments. The study will also collect information about any complications you experience during and after your surgery. The entire study follows your standard cancer treatment schedule.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
United States
Sponsor
Wake Forest University Health Sciences
Collaborators
Atrium Health Wake Forest Baptist
Enrollment target
~35 participants
Started
July 2025
Primary completion
November 2026
Age range
55 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Sydney McEntire, RN
Wake Forest University Health Sciences
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.