Testing a new medication to protect insulin-producing cells in newly diagnosed type 1 diabetes

This trial is testing baricitinib, a medication that may help protect the insulin-producing cells (called beta cells) in people who have recently been diagnosed with type 1 diabetes. The goal is to see whether the medication can help your body preserve these cells longer, which could mean better blood sugar control and less insulin needed over time. About 300 people will participate, with some receiving the medication and others receiving a placebo (an inactive pill).

In type 1 diabetes, the body's immune system attacks insulin-producing cells, but some cells usually survive after diagnosis. This medication is designed to calm down that immune attack and help preserve the remaining cells, which could significantly improve how people manage their diabetes in the long term.